Description
Product Characteristics:
Aliases: COX 17 antibody, COX17 antibody, COX17 cytochrome c oxidase assembly homolog (S. cerevisiae) antibody, COX17 cytochrome c oxidase assembly homolog antibody, COX17 homolog cytochrome c oxidase assembly protein antibody, COX17_HUMAN antibody, cytochrome c oxidase assembly protein cox17 homolog antibody, Cytochrome c oxidase copper chaperone antibody, Human homolog of yeast mitochondrial copper recruitment antibody, MGC104397 antibody, MGC117386 antibody, OTTHUMP00000215284 antibody, OTTHUMP00000215285 antibody
Target Information: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq, Jul 2008]